Barbering in mice: a model for trichotillomania.
نویسندگان
چکیده
منابع مشابه
Preventing, treating, and predicting barbering: A fundamental role for biomarkers of oxidative stress in a mouse model of Trichotillomania
Barbering, where a "barber" mouse plucks hair from its cagemates or itself, is both a spontaneously occurring abnormal behavior in mice and a well validated model of Trichotillomania (TTM). N-Acetylcysteine, (NAC) a cysteine derived food additive, is remarkably effective in treating TTM patients, but its mechanism of action is unknown. Reactive Oxygen Species (ROS), also known as free radicals,...
متن کاملDevelopment and Validation of a Metacognitive-Cognitive-Behavioral Model for Explaining Trichotillomania
Background & Aims: Trichotillomania (TTM) is an unknown disorder and resistant to treatment. The purpose of this study was to develop and validate the new metacognitive-cognitive-behavioral model for trichotillomania. Methods: The present study was a description and correlation study. In this study, 635 participants (304 male and 331 female) were selected. The participants completed the Massach...
متن کاملThe Dalila effect: C57BL6 mice barber whiskers by plucking.
Group-housed laboratory mice are frequently found with their whiskers and facial hair removed. It has been proposed that dominant mice are responsible for barbering the hair of the recipient (the Dalila effect), and early studies suggest that the hair is removed by nibbling. In the present study, pairs of C57BL6 mice, composed of a barber and recipient, were separated to allow hair to regrow. T...
متن کاملUlcerative dermatitis (UD) is a common syndrome of unknown etiology that results in profound morbidity in C57BL/6 mice and strains on a C57BL/6 background.18,26,41 Ulcerations
166 Ulcerative dermatitis (UD) is a common syndrome of unknown etiology that results in profound morbidity in C57BL/6 mice and strains on a C57BL/6 background.18,26,41 Ulcerations generally present on the dorsal scapulae, although torso, shoulder, and facial lesions are seen also, and may be single or multifocal in distribution.2,18,22 The lesions are due to severe pruritus-induced self-trauma,...
متن کاملEnvironmental enrichment reduces the likelihood of alopecia in adult C57BL/6J mice.
Barbering (incessant grooming) is an abnormal behavior causing alopecia and commonly affects various strains of laboratory mice, including C57BL/6J. Barbering-induced alopecia is a potential symptom of brain impairment and can indicate a stressful environment. We compared alopecia prevalence and severity in mice housed in enriched or standard cages. Providing an enriched environment delayed the...
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ورودعنوان ژورنال:
- BMJ
دوره 331 7531 شماره
صفحات -
تاریخ انتشار 2005